Burns and donor site treatment using allogeneic type I collagen

Introduction. The search for methods to reduce the time of treatment burns and wounds donor sites currently remains relevant.Aim. Objective this retrospective study was evaluate effectiveness local II–IIIA degree site with dressings based on allogeneic type I collagen.Material methods. included 434 patients hospitalized in 2018–2021. Collagen were used 280 (234 46 wounds); 154 comparison group received traditional accordance standards care burns. Patients did not differ statistically significantly age area (general, superficial, deep). Lyophilized, sterile collagen (RC No. FSR 2009/06370 December 8, 2014) manufactured TU 9393-002-01967081-2008 by Department Tissue Preservation Graft Manufacturing our Institute. We compared timing wound epithelialization when using versus conventional treatment, pain intensity as assessed visual analogue scale pain.Results. terms complete burn made 10 (7;12) days collagenbased used, 18 (14;20) without collagen, difference being significant (p<0.001). Epithelialization took 9 (8;10) dressings, 11 (10;12) after application lower 1, 4, 7 than (p<0.001, p<0.001, p=0.003, respectively).Conclusion. use superficial reduces re-epithelialization, decreases wounds, which proves greater efficacy method.